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We treated four patients affected by orthostatic tremor(OT)with gabapentin in increasing doses(300 to 2,400 mg/d).OT was evaluated with patients self-monitoring scales,tremor rating scales,electromyography(EMG)showing the 14-to 18 Hz frequencies,and EMG frequency analysis.All patients had transitory responses to clonazepam.Gabapentin induced disappearance of OT in three patients and consistent reduction in one.Crossover to placebo induced reappearance of tremor. |
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